A4GNT Antikörper (AA 131-180)

Produktnummer ABIN1386286

Produktdetails anti-A4GNT Antikörper

Target: A4GNT (alpha-1,4-N-Acetylglucosaminyltransferase (A4GNT))

Bindungsspezifität: AA 131-180

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser A4GNT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human A4GNT

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu A4GNT

Target: A4GNT (alpha-1,4-N-Acetylglucosaminyltransferase (A4GNT))

Andere Bezeichnung: A4GNT (A4GNT Produkte)

Synonyme: A4GNT antikoerper, a4gnt antikoerper, MGC116495 antikoerper, ALPHA4GNT antikoerper, alpha4GnT antikoerper, AV080780 antikoerper, Alpha4gnt antikoerper, Gm798 antikoerper, alpha-1,4-N-acetylglucosaminyltransferase antikoerper, alpha-1,4-N-acetylglucosaminyltransferase L homeolog antikoerper, A4GNT antikoerper, a4gnt antikoerper, a4gnt.L antikoerper, A4gnt antikoerper

Hintergrund:

Synonyms: 4-N-acetylglucosaminyltransferase, A4GCT_HUMAN, A4GNT, Alpha 1 4 N acetylglucosaminyltransferase, Alpha-1, Alpha4GnT, EC 2.4.1., MGC149493.

Background: Alpha 1,4-N-acetylflucosaminyltransferase (Alpha4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan). Alpha4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcalpha1-4Galbeta1-R, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Alpha4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity. It is expressed in stomach and pancreas, as well as in gastric cancer cells. Alpha4Gn-T is not expressed in peripheral blood cells, making it a useful biomarker for pancreatic cancer. Alpha4Gn-T and Mucin 6 expression is upregulated in the gastric mucosa of H.pylori infected patients, which suggest the involvement of ?Gn-T in defense against H. pylori infection.

Gen-ID: 51146