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Transferrin Receptor Antikörper (AA 621-720)

TFRC Reaktivität: Human, Maus FACS, WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386360
  • Target Alle Transferrin Receptor (TFRC) Antikörper anzeigen
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Bindungsspezifität
    • 15
    • 14
    • 11
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 621-720
    Reaktivität
    • 201
    • 88
    • 30
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 115
    • 111
    • 34
    • 1
    • 1
    Kaninchen
    Klonalität
    • 161
    • 99
    • 1
    Polyklonal
    Konjugat
    • 113
    • 29
    • 23
    • 15
    • 11
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Transferrin Receptor Antikörper ist unkonjugiert
    Applikation
    • 155
    • 135
    • 76
    • 70
    • 53
    • 41
    • 24
    • 21
    • 19
    • 12
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Pig,Horse,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Transferrin receptor
    Isotyp
    IgG
    Top Product
    Discover our top product TFRC Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Andere Bezeichnung
    Transferrin receptor (TFRC Produkte)
    Synonyme
    Trfr antikoerper, LOC100219280 antikoerper, tfr antikoerper, cd71 antikoerper, tfr1 antikoerper, trfr antikoerper, CD71 antikoerper, T9 antikoerper, TFR antikoerper, TFR1 antikoerper, TR antikoerper, TRFR antikoerper, p90 antikoerper, 2610028K12Rik antikoerper, AI195355 antikoerper, AI426448 antikoerper, AU015758 antikoerper, E430033M20Rik antikoerper, Mtvr-1 antikoerper, Mtvr1 antikoerper, transferrin receptor antikoerper, TFRC antikoerper, Tfrc antikoerper, tfrc antikoerper
    Hintergrund

    Synonyms: T9, TR, TFR, p90, CD71, TFR1, TRFR, Transferrin receptor protein 1, TFRC

    Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

    Gen-ID
    7037
    UniProt
    P02786
    Pathways
    Transition Metal Ion Homeostasis
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