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LAT Antikörper (pTyr161)

Name: LAT Antikörper (pTyr161)
SKU: ABIN1386362
Price: 384.62 EUR
Availability: InStock

LAT Reaktivität: Human ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-Phospho-LAT (Tyr161) Polyclonal Antibody, Unconjugated (ABIN1386362) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (LAT Antikörper (pTyr161))

IHC

Paraformaldehyde-fixed, paraffin embedded rat spleen tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-LAT (Tyr161) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (LAT Antikörper (pTyr161))

IHC (p)

2 Abbildungen

Produktnummer ABIN1386362

Datenblatt (PDF)

Target Alle LAT Antikörper anzeigen

LAT (Linker For Activation of T Cells (LAT))
Bindungsspezifität
20

19

15

8

8

8

7

7

4

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr161
Reaktivität
143

61

43

1
Human
Wirt
125

19

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
128

19
Polyklonal
Konjugat
70

7

6

6

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

2
Dieser LAT Antikörper ist unkonjugiert
Applikation
78

45

38

38

15

13

10

8

6

4

2

2

2

1

1

1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie

Human,Mouse,Rat,Cow

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161

Isotyp

IgG

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Applikationshinweise

ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Target

LAT (Linker For Activation of T Cells (LAT))

Andere Bezeichnung

LAT (LAT Produkte)

Synonyme

LAT antikoerper, lat antikoerper, LAT1 antikoerper, pp36 antikoerper, linker for activation of T-cells antikoerper, linker for activation of T cells antikoerper, LAT antikoerper, lat antikoerper, Lat antikoerper

Hintergrund

Synonyms: LAT1, pp36, Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, p36-38, LAT
Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Gen-ID

27040

UniProt

O43561

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung