CDH18 Antikörper (AA 301-400)
-
- Target Alle CDH18 Antikörper anzeigen
- CDH18 (Cadherin 18, Type 2 (CDH18))
-
Bindungsspezifität
- AA 301-400
-
Reaktivität
- Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CDH18 Antikörper ist unkonjugiert
-
Applikation
- ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CDH18
- Isotyp
- IgG
- Top Product
- Discover our top product CDH18 Primärantikörper
-
-
- Applikationshinweise
-
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- CDH18 (Cadherin 18, Type 2 (CDH18))
- Andere Bezeichnung
- CDH18 (CDH18 Produkte)
- Synonyme
- B230220E17Rik antikoerper, Cdh14l antikoerper, CDH14 antikoerper, CDH14L antikoerper, CDH24 antikoerper, cadherin 18 antikoerper, Cdh18 antikoerper, CDH18 antikoerper
- Hintergrund
-
Synonyms: CAD18_HUMAN, Cadherin 14, Cadherin14, Cadherin 18, Cadherin18, Cadherin 18, type 2, Cadherin-14, Cadherin-18, CDH14, CDH14L, CDH18, CDH24, EY CADHERIN.
Background: The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding events that are critical to the maintenance of cell structure and morphogenesis. EY-cadherin, also known as CDH18 (cadherin 18), CDH14 (cadherin 14), CDH24 or CDH14L, is a 790 amino acid single-pass type I membrane protein that contains five cadherin domains. One of several members of the cadherin superfamily, EY-cadherin functions as a type II classical cadherin that is expressed specifically in the central nervous system (CNS), where it plays a role in cell-cell binding events. Specifically, EY-cadherin is thought to be involved in axon guidance and outgrowth, as well as synaptic adhesion within the CNS. EY-cadherin contains a highly conserved C-terminal domain characteristic of all cadherins, but lacks the HAV cell adhesion sequence that is specific to type I cadherins. The gene encoding EY-cadherin is located within a region on chromosome five that is commonly deleted in carcinomas, implicating EY-cadherin as a potential tumor suppressor.
- Pathways
- Cell-Cell Junction Organization
-