ABCA7 Antikörper (AA 251-350)
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- Target Alle ABCA7 Antikörper anzeigen
- ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
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Bindungsspezifität
- AA 251-350
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABCA7 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ABCA7
- Isotyp
- IgG
- Top Product
- Discover our top product ABCA7 Primärantikörper
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- Applikationshinweise
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
- Andere Bezeichnung
- ABCA7 (ABCA7 Produkte)
- Synonyme
- ABCX antikoerper, Abc51 antikoerper, ABCA-SSN antikoerper, ABCA7 antikoerper, ATP-binding cassette, sub-family A (ABC1), member 7 antikoerper, ATP binding cassette subfamily A member 7 antikoerper, ATP-binding cassette sub-family A member 7 antikoerper, Abca7 antikoerper, ABCA7 antikoerper, LOC100088822 antikoerper
- Hintergrund
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Synonyms: ABC transporter ABCA7, ABC transporter member 7, ABCA SSN, ABCX, ATP binding cassette sub family A ABC1 member 7, ATP binding cassette sub family A member 7, ATP binding Cassette Transporter A7,FLJ40025, Macrophage ABC transporter, ABCA7_HUMAN.
Background: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
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