Syntaxin 6 Antikörper (AA 161-255)

Produktnummer ABIN1386482

Produktdetails anti-Syntaxin 6 Antikörper

Target: Syntaxin 6 (STX6)

Bindungsspezifität: AA 161-255

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Syntaxin 6 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Syntaxin 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Syntaxin 6

Target: Syntaxin 6 (STX6)

Andere Bezeichnung: Syntaxin 6 (STX6 Produkte)

Synonyme: CG7736 antikoerper, CT23545 antikoerper, Dm Syx6 antikoerper, DmSyx6 antikoerper, Dmel\\CG7736 antikoerper, SYN6 antikoerper, SYX6/10 antikoerper, Syx antikoerper, MGC78971 antikoerper, MGC132090 antikoerper, STX6 antikoerper, fb51b08 antikoerper, wu:fb51b08 antikoerper, zgc:110658 antikoerper, si:dkey-121a11.2 antikoerper, LOC734102 antikoerper, Syx6 antikoerper, Bmsyx6 antikoerper, Syntaxin-6 antikoerper, 2310039E05Rik antikoerper, 2410005I16Rik antikoerper, AA437559 antikoerper, AI415714 antikoerper, AI845861 antikoerper, Syntaxin 6 antikoerper, syntaxin 6 L homeolog antikoerper, syntaxin 6 antikoerper, Syx6 antikoerper, stx6.L antikoerper, STX6 antikoerper, stx6 antikoerper, Stx6 antikoerper

Hintergrund:

Synonyms: STX 6, STX6, STX-6, STX6_HUMAN, Syntaxin-6, Syntaxin6.

Background: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.

Pathways: Synaptic Vesicle Exocytosis