BBS10 Antikörper (AA 51-130)
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- Target Alle BBS10 Antikörper anzeigen
- BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
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Bindungsspezifität
- AA 51-130
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BBS10 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human BBS10
- Isotyp
- IgG
- Top Product
- Discover our top product BBS10 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
- Andere Bezeichnung
- BBS10 (BBS10 Produkte)
- Synonyme
- MGC84945 antikoerper, si:dkey-30c15.16 antikoerper, C12orf58 antikoerper, RGD1560748 antikoerper, 1300007O09Rik antikoerper, AI452285 antikoerper, Bardet-Biedl syndrome 10 antikoerper, Bardet-Biedl syndrome 10 L homeolog antikoerper, Bardet-Biedl syndrome 10 (human) antikoerper, BBS10 antikoerper, bbs10.L antikoerper, bbs10 antikoerper, Bbs10 antikoerper
- Hintergrund
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Synonyms: Bardet Biedl syndrome 10 protein, Bardet Biedl syndrome 10 protein homolog, C12orf58, FLJ23560, RGD1560748, BBS10_HUMAN.
Background: Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. Other associated clinical findings in BBS patients include diabetes, hypertension, and congenital heart defects. BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14. Many BBS genes encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS10 (Bardet-Biedl syndrome 10), also known as chromosome 12 open reading fame 58, C12orf58 or FLJ23560, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family. BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis. Inhibition of BBS10 has been found to impair ciliogenesis, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation. The gene encoding BBS10 contains two exons and maps to human chromosome 12q21.2.
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