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BBS10 Antikörper (AA 51-130)

BBS10 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386551
  • Target Alle BBS10 Antikörper anzeigen
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 51-130
    Reaktivität
    • 46
    • 2
    • 1
    • 1
    Human
    Wirt
    • 45
    • 1
    Kaninchen
    Klonalität
    • 46
    Polyklonal
    Konjugat
    • 13
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BBS10 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 19
    • 13
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BBS10
    Isotyp
    IgG
    Top Product
    Discover our top product BBS10 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    Andere Bezeichnung
    BBS10 (BBS10 Produkte)
    Synonyme
    MGC84945 antikoerper, si:dkey-30c15.16 antikoerper, C12orf58 antikoerper, RGD1560748 antikoerper, 1300007O09Rik antikoerper, AI452285 antikoerper, Bardet-Biedl syndrome 10 antikoerper, Bardet-Biedl syndrome 10 L homeolog antikoerper, Bardet-Biedl syndrome 10 (human) antikoerper, BBS10 antikoerper, bbs10.L antikoerper, bbs10 antikoerper, Bbs10 antikoerper
    Hintergrund

    Synonyms: Bardet Biedl syndrome 10 protein, Bardet Biedl syndrome 10 protein homolog, C12orf58, FLJ23560, RGD1560748, BBS10_HUMAN.

    Background: Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. Other associated clinical findings in BBS patients include diabetes, hypertension, and congenital heart defects. BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14. Many BBS genes encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS10 (Bardet-Biedl syndrome 10), also known as chromosome 12 open reading fame 58, C12orf58 or FLJ23560, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family. BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis. Inhibition of BBS10 has been found to impair ciliogenesis, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation. The gene encoding BBS10 contains two exons and maps to human chromosome 12q21.2.

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