ALDH3A2 Antikörper (AA 101-200)

Produktnummer ABIN1386584

Produktdetails anti-ALDH3A2 Antikörper

Target: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDH3A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ALDH3A2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ALDH3A2

Target: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Andere Bezeichnung: ALDH3A2 (ALDH3A2 Produkte)

Synonyme: ALDH10 antikoerper, FALDH antikoerper, SLS antikoerper, AI194803 antikoerper, Ahd-3 antikoerper, Ahd-3r antikoerper, Ahd3 antikoerper, Ahd3-r antikoerper, Aldh4 antikoerper, Aldh4-r antikoerper, ALDH-III antikoerper, CG11140 antikoerper, CT41571 antikoerper, Dhap antikoerper, Dmel\\CG11140 antikoerper, l(2)03610 antikoerper, Aldh-III antikoerper, aldh3a2 antikoerper, wu:fc06b11 antikoerper, zgc:92064 antikoerper, ALDH3A2 antikoerper, aldehyde dehydrogenase 3 family member A2 antikoerper, aldehyde dehydrogenase family 3, subfamily A2 antikoerper, aldehyde dehydrogenase 3 family, member A2 antikoerper, Aldehyde dehydrogenase type III antikoerper, fatty aldehyde dehydrogenase antikoerper, aldehyde dehydrogenase 3 family, member A2a antikoerper, aldehyde dehydrogenase 3 family member A2 S homeolog antikoerper, aldH antikoerper, ALDH3A2 antikoerper, Aldh3a2 antikoerper, Aldh-III antikoerper, PTRG_02589 antikoerper, aldh3a2 antikoerper, aldh3a2a antikoerper, aldh3a2.S antikoerper, aldH antikoerper

Hintergrund:

Synonyms: Ahd 3, Ahd 3r, Ahd3, Ahd3 r, AL3A2_HUMAN, Aldehyde dehydrogenase 10, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase 3 family, member A2, Aldehyde dehydrogenase family 3 member A2, Aldehyde dehydrogenase family 3, subfamily A2, Aldehyde dehydrogenase, family 3, subfamily A, member 2, ALDH10, Aldh3, ALDH3A2, Aldh4, Aldh4 r, Aldh4r, FALDH, Fatty aldehyde dehydrogenase, FLJ20851, Microsomal aldehyde dehydrogenase, msALDH, SLS.

Background: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH3A2 (aldehyde dehydrogenase 3 family, member A2), also known as SLS, FALDH or ALDH10, is a 485 amino acid single-pass membrane protein that localizes to the cytoplasmic side of the endoplasmic reticulum and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH3A2 catalyzes the NAD+-dependent oxidation of long-chain aliphatic aldehydes to fatty acids, a process that is necessary for detoxification and lipid metabolism. Defects in the gene encoding ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS), an autosomal recessive neurocutaneous disorder characterized by severe mental retardation, seizures and speech defects. Multiple isoforms of ALDH3A2 exist due to alternative splicing events.