NPAS3 Antikörper (AA 21-120)
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- Target Alle NPAS3 Antikörper anzeigen
- NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
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Bindungsspezifität
- AA 21-120
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NPAS3 Antikörper ist unkonjugiert
- Applikation
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NPAS3
- Isotyp
- IgG
- Top Product
- Discover our top product NPAS3 Primärantikörper
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- Applikationshinweise
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
- Andere Bezeichnung
- NPAS3 (NPAS3 Produkte)
- Synonyme
- trh antikoerper, mop6 antikoerper, pasd6 antikoerper, MGC145768 antikoerper, MOP6 antikoerper, PASD6 antikoerper, bHLHe12 antikoerper, 4930423H22Rik antikoerper, neuronal PAS domain protein 3 antikoerper, npas3 antikoerper, NPAS3 antikoerper, Npas3 antikoerper
- Hintergrund
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Synonyms: Basic helix loop helix PAS protein MOP6, Basic-helix-loop-helix-PAS protein MOP6, bHLHe12, Class E basic helix-loop-helix protein 12, FLJ10003, FLJ11138, FLJ11605, Member of PAS protein 6, MOP 6, MOP6, Neuronal PAS domain containing protein 3, Neuronal PAS domain protein 3, Neuronal PAS domain-containing protein 3, Neuronal PAS3, NPAS 3, NPAS3, NPAS3_HUMAN, PAS domain-containing protein 6, PASD 6, PASD6.
Background: The Per-Arnt-Sim (PAS) domain is a 270 amino acid motif that mediates associations among various PAS family transcription factors. The PAS family contains neuronal specific transcription factors known as NPAS1, NPAS2 and NPAS3, which are involved the development and maintenance of learning and memory pathways. NPAS1 regulates erythropoietin expression in developing brain. NPAS2, also designated PAS 4/MOP4, associates with MOP3 to activate transcription. NPAS3, which localizes to the nucleus and is ubiquitously expressed in the adult brain, may be involved in neurogenesis and may control regulatory pathways relevant to psychotic illness and to schizophrenia. It regulates tracheal cell fates in the embryo and is necessary for the development of the posterior spiracles and the salivary gland duct. NPAS3 contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. Efficient DNA binding by NPAS2 requires dimerization with another bHLH protein.
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