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NPAS3 Antikörper (AA 21-120)

NPAS3 Reaktivität: Human ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386604
  • Target Alle NPAS3 Antikörper anzeigen
    NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 6
    Kaninchen
    Klonalität
    • 6
    Polyklonal
    Konjugat
    • 6
    Dieser NPAS3 Antikörper ist unkonjugiert
    Applikation
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NPAS3
    Isotyp
    IgG
    Top Product
    Discover our top product NPAS3 Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
    Andere Bezeichnung
    NPAS3 (NPAS3 Produkte)
    Synonyme
    trh antikoerper, mop6 antikoerper, pasd6 antikoerper, MGC145768 antikoerper, MOP6 antikoerper, PASD6 antikoerper, bHLHe12 antikoerper, 4930423H22Rik antikoerper, neuronal PAS domain protein 3 antikoerper, npas3 antikoerper, NPAS3 antikoerper, Npas3 antikoerper
    Hintergrund

    Synonyms: Basic helix loop helix PAS protein MOP6, Basic-helix-loop-helix-PAS protein MOP6, bHLHe12, Class E basic helix-loop-helix protein 12, FLJ10003, FLJ11138, FLJ11605, Member of PAS protein 6, MOP 6, MOP6, Neuronal PAS domain containing protein 3, Neuronal PAS domain protein 3, Neuronal PAS domain-containing protein 3, Neuronal PAS3, NPAS 3, NPAS3, NPAS3_HUMAN, PAS domain-containing protein 6, PASD 6, PASD6.

    Background: The Per-Arnt-Sim (PAS) domain is a 270 amino acid motif that mediates associations among various PAS family transcription factors. The PAS family contains neuronal specific transcription factors known as NPAS1, NPAS2 and NPAS3, which are involved the development and maintenance of learning and memory pathways. NPAS1 regulates erythropoietin expression in developing brain. NPAS2, also designated PAS 4/MOP4, associates with MOP3 to activate transcription. NPAS3, which localizes to the nucleus and is ubiquitously expressed in the adult brain, may be involved in neurogenesis and may control regulatory pathways relevant to psychotic illness and to schizophrenia. It regulates tracheal cell fates in the embryo and is necessary for the development of the posterior spiracles and the salivary gland duct. NPAS3 contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. Efficient DNA binding by NPAS2 requires dimerization with another bHLH protein.

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