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mGluR1 + mGluR5 Antikörper (AA 501-600)

mGluR1/5 Reaktivität: Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386658
  • Target Alle mGluR1 + mGluR5 (mGluR1/5) Produkte
    mGluR1 + mGluR5 (mGluR1/5) (Glutamate Receptor, Metabotropic 5/1 (mGluR1/5))
    Bindungsspezifität
    • 16
    • 5
    • 3
    • 2
    AA 501-600
    Reaktivität
    • 23
    • 22
    • 21
    • 2
    Maus
    Wirt
    • 18
    • 8
    Kaninchen
    Klonalität
    • 18
    • 8
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser mGluR1 + mGluR5 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 14
    • 13
    • 13
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    mGluR1 + mGluR5 (mGluR1/5) (Glutamate Receptor, Metabotropic 5/1 (mGluR1/5))
    Andere Bezeichnung
    MGLUR1 + MGLUR5 (mGluR1/5 Produkte)
    Hintergrund

    Synonyms: MGLUR1+MGLUR5, GPRC1A, GPRC1E, GRM1, GRM1A, GRM5, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 5, mGlu1, mGlu5, MGLUR1, MGLUR1A, MGLUR5, MGLUR5B, GRM1_HUMAN, GRM5_HUMAN.

    Background: Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a. The Group-II receptors in include mGluR2 and mGluR3.

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