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DLGAP4 Antikörper (AA 261-370)

DLGAP4 Reaktivität: Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386704
  • Target Alle DLGAP4 Antikörper anzeigen
    DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))
    Bindungsspezifität
    • 14
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    AA 261-370
    Reaktivität
    • 26
    • 15
    • 15
    Maus, Ratte
    Wirt
    • 38
    • 2
    Kaninchen
    Klonalität
    • 40
    Polyklonal
    Konjugat
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DLGAP4 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 16
    • 12
    • 12
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SAPAP4/DLGAP4
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))
    Andere Bezeichnung
    SAPAP4/DLGAP4 (DLGAP4 Produkte)
    Synonyme
    DAP4 antikoerper, DLP4 antikoerper, RP5-977B1.6 antikoerper, SAPAP4 antikoerper, MGC155295 antikoerper, DKFZp469I1627 antikoerper, AI225853 antikoerper, BC024558 antikoerper, DAP-4 antikoerper, SAPAP-4 antikoerper, Sapap4 antikoerper, WBP16 antikoerper, Dap4 antikoerper, DLG associated protein 4 antikoerper, discs, large (Drosophila) homolog-associated protein 4 antikoerper, discs, large homolog-associated protein 4 (Drosophila) antikoerper, DLGAP4 antikoerper, dlgap4 antikoerper, Dlgap4 antikoerper
    Hintergrund

    Synonyms: DAP 4, DAP-4, DAP4, Discs, large Drosophila homolog associated protein 4, Disks large associated protein 4, Disks large-associated protein 4, DLGAP4, DLGP4_HUMAN, DLP4, PSD 95/SAP90 binding protein 4, PSD-95/SAP90-binding protein 4, RP5-977B1.6, SAP90/PSD-95-associated protein 4, SAPAP 4, SAPAP-4, SAPAP4.

    Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP4 is a 992 amino acid protein that likely localizes to the postsynaptic membrane of neurons to enhance neuronal signaling. SAPAP4 could act as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP4, DLGAP4, maps to human chromosome 20. Comprising approximately 2 % of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

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