MYF5 Antikörper (pSer49)

Produktnummer ABIN1386790

Produktdetails anti-MYF5 Antikörper

Target: MYF5 (Myogenic Factor 5 (MYF5))

Bindungsspezifität: pSer49

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MYF5 around the phosphorylation site of Ser49

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MYF5

Target: MYF5 (Myogenic Factor 5 (MYF5))

Andere Bezeichnung: Myf5 (MYF5 Produkte)

Synonyme: bHLHc2 antikoerper, B130010J22Rik antikoerper, Myf-5 antikoerper, cb641 antikoerper, myf-5 antikoerper, zgc:110509 antikoerper, Xmyf5 antikoerper, Xmyf-5 antikoerper, MYF5 antikoerper, xmyf-5 antikoerper, MYF-5 antikoerper, myogenic factor 5 antikoerper, myogenic factor 5 L homeolog antikoerper, MYF5 antikoerper, Myf5 antikoerper, myf5 antikoerper, myf5.L antikoerper

Hintergrund:

Synonyms: Myf5 phospho S49, Myf5 phospho Ser49, p-Myf5phospho S49, p-Myf5phospho Ser49, Myf-5 bHLHc2, Class C basic helix loop helix protein 2, Class C basic helix-loop-helix protein 2, Myf 5, Myf-5, Myf5, MYF5_HUMAN, Myogenic factor 5.

Background: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development include Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Of interest, most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes.

Gen-ID: 4617

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development