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PANK1 Antikörper

PANK1 Reaktivität: Human, Maus, Ratte WB, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386809
  • Target Alle PANK1 Antikörper anzeigen
    PANK1 (Pantothenate Kinase 1 (PANK1))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 43
    • 3
    Kaninchen
    Klonalität
    • 46
    Polyklonal
    Konjugat
    • 18
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PANK1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 19
    • 12
    • 10
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PANK1
    Isotyp
    IgG
    Top Product
    Discover our top product PANK1 Primärantikörper
  • Applikationshinweise
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    PANK1 (Pantothenate Kinase 1 (PANK1))
    Andere Bezeichnung
    PANK1 (PANK1 Produkte)
    Synonyme
    PANK antikoerper, 4632412I06Rik antikoerper, 5430426F23Rik antikoerper, Pank antikoerper, Pank1a antikoerper, Pank1b antikoerper, panK1beta antikoerper, PANK1 antikoerper, im:7149302 antikoerper, wu:fb51a11 antikoerper, zgc:158746 antikoerper, ATCOAA antikoerper, ATPANK1 antikoerper, T13D8.31 antikoerper, T13D8_31 antikoerper, pantothenate kinase 1 antikoerper, DKFZp469J1021 antikoerper, fb79e08 antikoerper, zgc:63556 antikoerper, wu:fb79e08 antikoerper, pantothenate kinase 1 antikoerper, pantothenate kinase 1b antikoerper, pantothenate kinase 1a antikoerper, PANK1 antikoerper, Pank1 antikoerper, pank1b antikoerper, EHI_183060 antikoerper, pank1a antikoerper
    Hintergrund

    Synonyms: coaA, hPanK, hPanK1, PANK, PANK1, PANK1_HUMAN, PANK1a, PANK1b, PanK1beta, Pantothenate kinase 1, Pantothenate kinase, Pantothenic acid kinase 1.

    Background: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA). Pantothenate kinase 1 (PANK1) is a 598 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK1 is strongly inhibited by acetyl-CoA and manyl-CoA, as well as by high concentration of non-esterified CoA (CoASH). Four known isoforms of PANK1 exist as a result of alternative splicing events. Of these isoforms, PANK1a and PANK1b have been identified as the catalytically active isoforms. Isoform PANK1a is most highly expressed in brain, heart, kidney, liver, skeletal muscle and kidney. Isoform PANK1b is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.

    Gen-ID
    53354
    UniProt
    Q8TE04
    Pathways
    Ribonucleoside Biosynthetic Process
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