PANK1 Antikörper

Produktnummer ABIN1386809

Produktdetails anti-PANK1 Antikörper

Target: PANK1 (Pantothenate Kinase 1 (PANK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PANK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PANK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu PANK1

Target: PANK1 (Pantothenate Kinase 1 (PANK1))

Andere Bezeichnung: PANK1 (PANK1 Produkte)

Synonyme: PANK antikoerper, 4632412I06Rik antikoerper, 5430426F23Rik antikoerper, Pank antikoerper, Pank1a antikoerper, Pank1b antikoerper, panK1beta antikoerper, PANK1 antikoerper, im:7149302 antikoerper, wu:fb51a11 antikoerper, zgc:158746 antikoerper, ATCOAA antikoerper, ATPANK1 antikoerper, T13D8.31 antikoerper, T13D8_31 antikoerper, pantothenate kinase 1 antikoerper, DKFZp469J1021 antikoerper, fb79e08 antikoerper, zgc:63556 antikoerper, wu:fb79e08 antikoerper, pantothenate kinase 1 antikoerper, pantothenate kinase 1b antikoerper, pantothenate kinase 1a antikoerper, PANK1 antikoerper, Pank1 antikoerper, pank1b antikoerper, EHI_183060 antikoerper, pank1a antikoerper

Hintergrund:

Synonyms: coaA, hPanK, hPanK1, PANK, PANK1, PANK1_HUMAN, PANK1a, PANK1b, PanK1beta, Pantothenate kinase 1, Pantothenate kinase, Pantothenic acid kinase 1.

Background: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA). Pantothenate kinase 1 (PANK1) is a 598 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK1 is strongly inhibited by acetyl-CoA and manyl-CoA, as well as by high concentration of non-esterified CoA (CoASH). Four known isoforms of PANK1 exist as a result of alternative splicing events. Of these isoforms, PANK1a and PANK1b have been identified as the catalytically active isoforms. Isoform PANK1a is most highly expressed in brain, heart, kidney, liver, skeletal muscle and kidney. Isoform PANK1b is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.

Gen-ID: 53354

UniProt: Q8TE04

Pathways: Ribonucleoside Biosynthetic Process