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FBXL12 Antikörper (AA 171-270)

FBXL12 Reaktivität: Human WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386844
  • Target Alle FBXL12 Antikörper anzeigen
    FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))
    Bindungsspezifität
    • 11
    • 8
    • 6
    • 2
    • 1
    AA 171-270
    Reaktivität
    • 24
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 23
    • 1
    Kaninchen
    Klonalität
    • 24
    Polyklonal
    Konjugat
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser FBXL12 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FbxL12
    Isotyp
    IgG
    Top Product
    Discover our top product FBXL12 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))
    Andere Bezeichnung
    FbxL12 (FBXL12 Produkte)
    Synonyme
    Fbl12 antikoerper, FBXL12 antikoerper, fbl12 antikoerper, 3110048D16Rik antikoerper, F-box and leucine rich repeat protein 12 antikoerper, F-box and leucine-rich repeat protein 12 antikoerper, RNI-like superfamily protein antikoerper, FBXL12 antikoerper, Fbxl12 antikoerper, fbxl12 antikoerper, AT3G07550 antikoerper
    Hintergrund

    Synonyms: F box and leucine rich repeat protein 12, F box protein FBL12, F box/LRR repeat protein 12, FBXL 12, FLJ20188, FXL12_HUMAN.

    Background: F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune responses, signaling cascades and developmental events) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚,B-å, and -catenin, for proteasomal degradation. FBL12 (F-box and leucine-rich repeat protein 12), also designated FBXL12, is a 326 amino acid protein that contains one F-box domain, five LRR (leucine-rich) repeats and exists as two alternatively spliced isoforms. FBL12 interacts with both Skp1 and CUL-1, and is encoded by a gene that maps to human chromosome 19p13.2.

    Gen-ID
    54850
    Pathways
    SARS-CoV-2 Protein Interaktom
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