FBXO7 Antikörper (AA 251-350)

Produktnummer ABIN1386851

Produktdetails anti-FBXO7 Antikörper

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Bindungsspezifität: AA 251-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO7 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FBXO7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FBXO7

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Andere Bezeichnung: FBXO7 (FBXO7 Produkte)

Synonyme: fbxo7 antikoerper, MGC80085 antikoerper, FBXO7 antikoerper, fbx7 antikoerper, MGC135804 antikoerper, MGC145325 antikoerper, ATFBP7 antikoerper, F-BOX PROTEIN 7 antikoerper, F-box protein 7 antikoerper, F8K7.20 antikoerper, F8K7_20 antikoerper, DKFZp469H0739 antikoerper, si:ch211-286m4.2 antikoerper, zgc:114096 antikoerper, FBX antikoerper, FBX07 antikoerper, FBX7 antikoerper, PARK15 antikoerper, PKPS antikoerper, 2410015K21Rik antikoerper, A230052G17Rik antikoerper, AI117679 antikoerper, AW260462 antikoerper, C85118 antikoerper, F-box protein 7 antikoerper, F-box protein 7 L homeolog antikoerper, FBXO7 antikoerper, fbxo7.L antikoerper, fbxo7 antikoerper, FBP7 antikoerper, Fbxo7 antikoerper

Hintergrund:

Synonyms: F box only protein 7, F box protein 7, F-box protein 7, FBX, FBX07, FBX7, PARK15, PKPS,

Background: FBXO7, also known as FBX, FBX7 or PKPS, is a 522 amino acid protein that contains one F-box domain and functions as a component of the SCF complex. Defects in the gene encoding FBXO7 are associated with parkinsonian-pyramidal syndrome (PKPS), a hypokinetic rigid disorder that exhibits Parkinsonian and pyramidal-associated symptoms.The FBXO7 gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

Gen-ID: 25793