UNC93B1 Antikörper (AA 451-550)
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- Target Alle UNC93B1 Antikörper anzeigen
- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
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Bindungsspezifität
- AA 451-550
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UNC93B1 Antikörper ist unkonjugiert
- Applikation
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human UNC93B
- Isotyp
- IgG
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- Applikationshinweise
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
- Andere Bezeichnung
- UNC93B (UNC93B1 Produkte)
- Synonyme
- UNC93 antikoerper, IIAE1 antikoerper, UNC93B antikoerper, Unc-93B1 antikoerper, Unc93b antikoerper, unc-93 homolog B1, TLR signaling regulator antikoerper, unc-93 homolog B1 (C. elegans) antikoerper, UNC93B1 antikoerper, Unc93b1 antikoerper
- Hintergrund
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Synonyms: IIAE1, UNC93, UNC93B, Unc-93B1, Protein unc-93 homolog B1, hUNC93B1, UNC93B1
Background: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.
- Gen-ID
- 81622
- UniProt
- Q9H1C4
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
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