BRMS1 Antikörper (AA 151-246)
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- Target Alle BRMS1 Antikörper anzeigen
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
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Bindungsspezifität
- AA 151-246
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BRMS1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human BRMS1
- Isotyp
- IgG
- Top Product
- Discover our top product BRMS1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- Andere Bezeichnung
- BRMS1 (BRMS1 Produkte)
- Synonyme
- MGC98869 antikoerper, BRMS1 antikoerper, BRMS1L antikoerper, AV003220 antikoerper, AW554636 antikoerper, si:zc188c22.3 antikoerper, si:zc194c5.2 antikoerper, wu:fb57b08 antikoerper, zgc:56414 antikoerper, breast cancer metastasis suppressor 1 antikoerper, breast cancer metastasis-suppressor 1 antikoerper, breast cancer metastasis suppressor 1 L homeolog antikoerper, BRMS1 antikoerper, Brms1 antikoerper, brms1.L antikoerper, brms1 antikoerper
- Hintergrund
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Synonyms: Breast cancer metastasis suppressor 1, Breast cancer metastasis-suppressor 1, BRMS-1, BRMS1_HUMAN, DKFZp564A063, MGC95128, AV003220, AW554636.
Background: Breast cancer metastasis-suppressor 1 (BRMS1) is 246 amino acid protein that acts as a mediator of metastasis suppression in several types of cancer including ovarian, lung, bladder, and murine mammary. BRMS1 mRNA is expressed in various tissues, including ovary, prostate, testis, and colon, but the protein is primarily detected in term placenta. BRMS1 suppresses metastasis without inhibiting tumorigenicity by modifying several metastasis-associated phenotypes. BRMS1 may participate in transcriptional regulation by binding to the mSin3/histone deacetylase complex. The expression of BRMS1 in certain cells increases connexin Cx43 expression and reduces connexin Cx32 expression. This produces a gap junction that increases intercellular communication, similar to those found in normal breast tissue. BRMS1 is stabilized by Hsp90 and may inhibit NF-_B activity.
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