ZNRF1 Antikörper
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- Target Alle ZNRF1 Antikörper anzeigen
- ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZNRF1 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ZNRF1
- Isotyp
- IgG
- Top Product
- Discover our top product ZNRF1 Primärantikörper
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- Applikationshinweise
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IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))
- Andere Bezeichnung
- ZNRF1 (ZNRF1 Produkte)
- Synonyme
- NIN283 antikoerper, B830022L21Rik antikoerper, Rnf42 antikoerper, Zrfp1 antikoerper, nin283 antikoerper, zgc:77896 antikoerper, zrfp1 antikoerper, zinc and ring finger 1 antikoerper, zinc and ring finger 1, E3 ubiquitin protein ligase S homeolog antikoerper, ZNRF1 antikoerper, Znrf1 antikoerper, znrf1 antikoerper, znrf1.S antikoerper
- Hintergrund
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Synonyms: E3 ubiquitin protein ligase ZNRF1, E3 ubiquitin-protein ligase ZNRF1, Nerve injury gene 283, Nerve injury induced gene 283 protein, Nerve injury-induced gene 283 protein, NIN283, Rnf42, Zinc and ring finger 1, zinc and ring finger protein 1, zinc finger and ring finger protein 1, Zinc/RING finger protein 1, ZNRF 1, znrf1, ZNRF1_HUMAN, Zrfp1.
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. ZNRF1 (zinc and ring finger 1), also known as NIN283, is a 227 amino acid protein that contains one RING-type zinc finger and localizes to the lysosome and the endosome, as well as to cytoplasmic vesicles and the peripheral membrane. Expressed primarily in nervous system tissue, but also present in testis and thymus, ZNRF1 functions as an E3 ubiquitin-protein ligase that is thought to play a role in the establishment and maintenance of neuronal plasticity. Multiple isoforms of ZNRF1 exist due to alternative splicing events.
- Gen-ID
- 84937
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