PSMD7 Antikörper

Produktnummer ABIN1387053

Produktdetails anti-PSMD7 Antikörper

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PSMD7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PSMD7

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Andere Bezeichnung: PSMD7 (PSMD7 Produkte)

Hintergrund:

Synonyms: 26S proteasome non ATPase regulatory subunit 7, 26S proteasome non-ATPase regulatory subunit 7, 26S proteasome regulatory subunit rpn8, 26S proteasome regulatory subunit S12, Moloney leukemia virus 34 proviral integration, MOV 34, MOV 34L, MOV34, Mov34 homolog, Mov34 protein homolog, MOV34L, P40 antibody Proteasome prosome macropain 26S subunit non ATPase 7, Proteasome 26S non ATPase subunit 7, Proteasome 26S S12, Proteasome subunit p40, PSD7_HUMAN, PSMD 7, PSMD-7, PSMD7, S12 antibody.

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Gen-ID: 5713

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway