CAF1p55 Antikörper

Produktnummer ABIN1387058

Produktdetails anti-CAF1p55 Antikörper

Target: CAF1p55 (CAF1) (Chromatin Assembly Factor 1 Subunit (CAF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAF1p55 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CAF1p55

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CAF1p55

Target: CAF1p55 (CAF1) (Chromatin Assembly Factor 1 Subunit (CAF1))

Andere Bezeichnung: CAF1p55 (CAF1 Produkte)

Hintergrund:

Synonyms: Caf 1, CAF-1, CAF-1 P55 subunit, CAF1 p55 subunit, CAF1A, CAF1P55, chaf1b, Chromatin assembly factor 1 p55 subunit, Chromatin assembly factor 1 p60 subunit, chromatin assembly factor 1 subunit, Chromatin assembly factor I, dCAF-1, dCAF1, Human chromatin assembly factor-I p55 subunit, Nucleosome remodeling factor 55 kDa subunit, NURF 55, NURF-55, p55, Probable histone binding protein Caf1, VPRBP_HUMAN.

Background: P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.

Gen-ID: 9730