SIRT5 Antikörper (AA 120-170)

Produktnummer ABIN1387080

Produktdetails anti-SIRT5 Antikörper

Target: SIRT5 (Sirtuin 5 (SIRT5))

Bindungsspezifität: AA 120-170

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SIRT5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SIRT5 Antikörper (ABIN1387080)

Takumida, Takumida, Anniko: "Localization of sirtuins in the mouse inner ear." in: Acta oto-laryngologica, Vol. 134, Issue 4, pp. 331-8, (2014) (PubMed).

Details zu SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Andere Bezeichnung: SIRT5 (SIRT5 Produkte)

Synonyme: SIR2L5 antikoerper, 0610012J09Rik antikoerper, 1500032M05Rik antikoerper, AV001953 antikoerper, zgc:92288 antikoerper, sirt5-a antikoerper, SIRT5 antikoerper, sir2l5 antikoerper, sirtuin 5 antikoerper, sirtuin 5 L homeolog antikoerper, SIRT5 antikoerper, Sirt5 antikoerper, sirt5 antikoerper, sirt5.L antikoerper, CC1G_00083 antikoerper

Hintergrund:

Synonyms: SIR2L5, NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5, SIR2-like protein 5, SIRT5

Background: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.

Gen-ID: 23408

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interaktom