CDC25C Antikörper (AA 290-340)

Produktnummer ABIN1387108

Produktdetails anti-CDC25C Antikörper

Target: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Bindungsspezifität: AA 290-340

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC25C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cdc25C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CDC25C Antikörper (ABIN1387108)

Ghate, Das, Chaudhuri, Panja, Mandal: "Sundew plant, a potential source of anti-inflammatory agents, selectively induces G2/M arrest and apoptosis in MCF-7 cells through upregulation of p53 and Bax/Bcl-2 ratio." in: Cell death discovery, Vol. 2, pp. 15062, (2016) (PubMed).

Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: "An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7." in: PLoS ONE, Vol. 8, Issue 12, pp. e82293, (2013) (PubMed).

Details zu CDC25C

Target: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Andere Bezeichnung: Cdc25C (CDC25C Produkte)

Synonyme: CDC25C antikoerper, cdc25 antikoerper, xcdc25c antikoerper, CDC25 antikoerper, PPP1R60 antikoerper, Cdc25 antikoerper, cdc25-3 antikoerper, xcdc25-3 antikoerper, cell division cycle 25C antikoerper, cell division cycle 25C S homeolog antikoerper, CDC25C antikoerper, cdc25c antikoerper, Cdc25c antikoerper, cdc25c.S antikoerper

Hintergrund:

Synonyms: CDC25, PPP1R6, M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C

Background: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.

Gen-ID: 995

UniProt: P30307

Pathways: Zellzyklus, M Phase