CLLD6 Antikörper

Produktnummer ABIN1387111

Produktdetails anti-CLLD6 Antikörper

Target: CLLD6 (C13orf1) (Chromosome 13 Open Reading Frame 1 (C13orf1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLLD6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLLD6/C13orf1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CLLD6

Target: CLLD6 (C13orf1) (Chromosome 13 Open Reading Frame 1 (C13orf1))

Andere Bezeichnung: CLLD6 (C13orf1 Produkte)

Synonyme: C13orf1 antikoerper, CLLD6 antikoerper, fd05e05 antikoerper, MGC56247 antikoerper, zgc:56247 antikoerper, wu:fd05e05 antikoerper, si:dz79f24.1 antikoerper, dZ79F24.1-001 antikoerper, si:busm1-79f24.1 antikoerper, C1H13orf1 antikoerper, c13orf1 antikoerper, Clld6 antikoerper, RGD1306437 antikoerper, 6330409N04Rik antikoerper, C12H13orf1 antikoerper, zgc:66415 antikoerper, zgc:77103 antikoerper, SPRY domain containing 7 antikoerper, SPRY domain containing 7a antikoerper, SPRY domain containing 7 S homeolog antikoerper, SPRY domain containing 7b antikoerper, SPRYD7 antikoerper, spryd7a antikoerper, spryd7.S antikoerper, spryd7 antikoerper, Spryd7 antikoerper, spryd7b antikoerper

Hintergrund:

Synonyms: Chromosome 13 open reading frame 1, Chronic lymphocytic leukemia deletion region gene 6 protein, CLL deletion region gene 6 protein, CLLD 6, CLLD6, Hypothetical protein LOC57213, SPRY7_HUMAN.

Background: CLLD6, is a 196 amino acid protein that contains one B30.2/SPRY domain. Expression of CLLD6 is found at highest levels in heart, skeletal muscle and testis, with lower levels found in thymus, peripheral blood leukocytes, lymph node and bone marrow. Existing as two alternatively spliced isoforms, CLLD6 maps to human chromosome 13, which comprises nearly 4 % of human DNA and contains about 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival.