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E4F1 Antikörper

E4F1 Reaktivität: Human, Maus, Ratte WB, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1387131
  • Target Alle E4F1 Antikörper anzeigen
    E4F1 (E4F Transcription Factor 1 (E4F1))
    Reaktivität
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 6
    • 4
    Kaninchen
    Klonalität
    • 8
    • 2
    Polyklonal
    Konjugat
    • 10
    Dieser E4F1 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human E4F1
    Isotyp
    IgG
    Top Product
    Discover our top product E4F1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    E4F1 (E4F Transcription Factor 1 (E4F1))
    Andere Bezeichnung
    E4F1 (E4F1 Produkte)
    Synonyme
    e4f antikoerper, MGC147041 antikoerper, E4F antikoerper, Dnase1l2 antikoerper, zgc:114190 antikoerper, E4F transcription factor 1 antikoerper, E4F transcription factor 1 S homeolog antikoerper, E4F1 antikoerper, e4f1 antikoerper, e4f1.S antikoerper, E4f1 antikoerper
    Hintergrund

    Synonyms: E4F, E4F transcription factor 1, isoform CRA_b, P120E4F transcription factor, E4F1_HUMAN.

    Background: E4F1, also known as E4F, is a 784 amino acid protein that localizes to both the nucleus and the cytoplasm and contains nine C2H2-type zinc fingers. Expressed ubiquitously in adult and fetal tissues, E4F1 exists as a homodimer that binds DNA and is thought to act as a transcriptional repressor and may also play a role in cell survival and growth via cell cycle control. Additionally, E4F1 is thought to function as a ubiquitin ligase that mediates the ubiquitination (and subsequent degradation) of target proteins and may be involved in the p53 tumor suppressor pathway. E4F1, which may be post-translationally phosphorylated or sumoylated, is subject to proteolytic cleavage which results in the creation of a short peptide with specific DNA binding capabilities.

    Gen-ID
    1877
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