Cadherin 5 Antikörper (AA 251-320)
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- Target Alle Cadherin 5 (CDH5) Antikörper anzeigen
- Cadherin 5 (CDH5)
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Bindungsspezifität
- AA 251-320
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cadherin 5 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Cow,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human VE Cadherin
- Isotyp
- IgG
- Top Product
- Discover our top product CDH5 Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Cadherin 5 (CDH5)
- Andere Bezeichnung
- VE Cadherin (CDH5 Produkte)
- Synonyme
- 7B4 antikoerper, AA408225 antikoerper, Cd144 antikoerper, VE-Cad antikoerper, VECD antikoerper, VEcad antikoerper, Vec antikoerper, wu:fc88a07 antikoerper, CD144 antikoerper, cadherin-5 antikoerper, cadherin 5 antikoerper, CDH5 antikoerper, Cdh5 antikoerper, cdh5 antikoerper
- Hintergrund
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Synonyms: 7B4, CD144, Cadherin-5, 7B4 antigen, Vascular endothelial cadherin, VE-cadherin, CDH5
Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
- Gen-ID
- 1003
- UniProt
- P33151
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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