DCLK1 Antikörper (AA 151-250)
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- Target Alle DCLK1 Antikörper anzeigen
- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
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Bindungsspezifität
- AA 151-250
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DCLK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DCAMKL1
- Isotyp
- IgG
- Top Product
- Discover our top product DCLK1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
- Andere Bezeichnung
- DCAMKL1 (DCLK1 Produkte)
- Synonyme
- DCLK1 antikoerper, DCAMKL1 antikoerper, dcamkl1 antikoerper, dclk1 antikoerper, wu:fc51f11 antikoerper, zgc:153709 antikoerper, MGC145348 antikoerper, CL1 antikoerper, CLICK1 antikoerper, DCDC3A antikoerper, DCLK antikoerper, 1700113D08Rik antikoerper, 2810480F11Rik antikoerper, AI836758 antikoerper, Click-I antikoerper, Cpg16 antikoerper, Dcamkl1 antikoerper, Dcl antikoerper, Dclk antikoerper, mKIAA0369 antikoerper, Ania4 antikoerper, doublecortin like kinase 1 antikoerper, doublecortin-like kinase 1a antikoerper, serine/threonine-protein kinase DCLK1 antikoerper, doublecortin-like kinase 2 antikoerper, doublecortin-like kinase 1 antikoerper, DCLK1 antikoerper, dclk1a antikoerper, LOC587664 antikoerper, dclk2 antikoerper, LOC100539645 antikoerper, Dclk1 antikoerper
- Hintergrund
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Synonyms: Calcium/calmodulin-dependent protein kinase type I-like CPG16, Cpg16, Dcl, Dclk, Dclk1, DCLK1_HUMAN, Doublecortin domain-containing protein 3A, Doublecortin-like and CAM kinase-like 1, Doublecortin-like kinase 1, KIAA0369, Serine/threonine-protein kinase DCAMKL1, Serine/threonine-protein kinase DCLK1.
Background: Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface, manifesting as severe mental retardation. Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, designated lissencephaly-1 protein (LIS1) and doublecortin. LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, and doublecortin contains a consensus Abl phosphorylation site. In addition, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin. All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration. The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, but its kinase activity does not appear to affect its microtubule polymerization activity.
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