Cullin 5 Antikörper (AA 701-780)

Produktnummer ABIN1387404

Produktdetails anti-Cullin 5 Antikörper

Target: Cullin 5 (CUL5)

Bindungsspezifität: AA 701-780

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cullin 5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cullin 5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Cullin 5

Target: Cullin 5 (CUL5)

Andere Bezeichnung: Cullin 5 (CUL5 Produkte)

Synonyme: cul5 antikoerper, wu:fd17d09 antikoerper, wu:fi20h12 antikoerper, xx:11fd17d09 antikoerper, zgc:66185 antikoerper, Xcullin5 antikoerper, CG1401 antikoerper, CUL5 antikoerper, Cul5 antikoerper, Cullin 5 antikoerper, Cullin5 antikoerper, Dmel\\CG1401 antikoerper, cul-5 antikoerper, vacm-1 antikoerper, vacm1 antikoerper, VACM-1 antikoerper, VACM1 antikoerper, 4921514I20Rik antikoerper, 8430423K24Rik antikoerper, AI852817 antikoerper, C030032G03Rik antikoerper, C330021I08Rik antikoerper, Cullin-5 antikoerper, cullin 5a antikoerper, cullin 5 L homeolog antikoerper, Cullin 5 antikoerper, cullin 5 antikoerper, Cullin-5 antikoerper, cul5a antikoerper, cul5.L antikoerper, Cul5 antikoerper, CUL5 antikoerper, cul5 antikoerper, cul-5 antikoerper

Hintergrund:

Synonyms: CUL 5, CUL-5, CUL5, CUL5_HUMAN, Cullin-5, Cullin5, VACM 1, VACM-1, VACM1, Vasopressin activated calcium mobilizing receptor 1, Vasopressin activated calcium mobilizing receptor, Vasopressin-activated calcium-mobilizing receptor 1.

Background: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

Gen-ID: 1729

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development