CTH Antikörper

Produktnummer ABIN1387469

Produktdetails anti-CTH Antikörper

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cystathionine gamma lyase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CTH Antikörper (ABIN1387469)

Shiina, Shima, Horii, Naitou, Nakamori, Sano, Shimizu: "Inhibitory action of hydrogen sulfide on esophageal striated muscle motility in rats." in: European journal of pharmacology, Vol. 771, pp. 123-9, (2016) (PubMed).

Details zu CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Andere Bezeichnung: CTH (CTH Produkte)

Synonyme: DYT17 antikoerper, DYT18 antikoerper, DYT9 antikoerper, EIG12 antikoerper, GLUT antikoerper, GLUT1 antikoerper, GLUT1DS antikoerper, HTLVR antikoerper, PED antikoerper, wu:fb48e03 antikoerper, wu:fb58d08 antikoerper, zgc:66001 antikoerper, zgc:85785 antikoerper, CTH antikoerper, 0610010I13Rik antikoerper, AI314617 antikoerper, BC019483 antikoerper, CSE antikoerper, Cys3 antikoerper, cysA antikoerper, SCQ11.03c antikoerper, DDBDRAFT_0190313 antikoerper, DDBDRAFT_0191318 antikoerper, DDB_0190313 antikoerper, DDB_0191318 antikoerper, H antikoerper, MGC75946 antikoerper, cystathionine gamma-lyase antikoerper, solute carrier family 2 member 1 antikoerper, cystathionase (cystathionine gamma-lyase) antikoerper, cystathionine gamma-lyase L homeolog antikoerper, CTH antikoerper, SLC2A1 antikoerper, cth antikoerper, Cth antikoerper, SCO3920 antikoerper, mlr1566 antikoerper, TA_RS00415 antikoerper, MAP_RS15640 antikoerper, SPO3344 antikoerper, CNN01730 antikoerper, Mmcs_1928 antikoerper, RHA1_RS31820 antikoerper, HNE_1212 antikoerper, MAV_3867 antikoerper, MSMEG_2394 antikoerper, Mvan_2142 antikoerper, SACE_6136 antikoerper, Mflv_4220 antikoerper, cysA antikoerper, cth.L antikoerper

Hintergrund:

Synonyms: CGL_HUMAN, CTH, Cystathionine gamma lyase, Cystathionine gamma-lyase, Cysteine desulfhydrase, Gamma cystathionase, Gamma-cystathionase, Homoserine deaminase, Homoserine dehydratase, MGC9471, CSE, Cystathionase.

Background: Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.

Gen-ID: 1491

Pathways: ER-Nucleus Signaling, Warburg Effekt