PDE7A Antikörper

Produktnummer ABIN1387580

Produktdetails anti-PDE7A Antikörper

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDE7A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C

Haltbarkeit: 12 months

Details zu PDE7A

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Andere Bezeichnung: Pde7a (PDE7A Produkte)

Synonyme: HCP1 antikoerper, PDE7 antikoerper, AU015378 antikoerper, AW047537 antikoerper, PDE7-1 antikoerper, cb1053 antikoerper, cb564 antikoerper, pde7al antikoerper, wu:fk53d11 antikoerper, wu:fk94g02 antikoerper, phosphodiesterase 7A antikoerper, phosphodiesterase 7A L homeolog antikoerper, PDE7A antikoerper, Pde7a antikoerper, pde7a.L antikoerper, pde7a antikoerper

Hintergrund:

Phosphodiesterases (PDE, also designated cyclic nucleotide phosphodiesterase) are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5'AMP. Phosphodiesterase type 3 isoforms, PDE3A and 3B, are expressed primarily in cardiovascular tissue and adipose tissue, respectively. PDE3A, is found in myocardium and platelets and PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.

Synonyms: HCP 1, HCP1, High affinity cAMP specic 3'5' cyclic phosphodiesterase 7A, High affinity cAMP-specic 3'', P2A, PDE 7, PDE 7A, PDE7, PDE71, PDE7A, PDE7A_HUMAN, Phosphodiesterase 7A, Phosphodiesterase isozyme 7, Phosphodiesterase7A, Rolipram insensitive phosphodiesterase type 7, TM 22, TM22, 5''-cyclic phosphodiesterase 7A.

Pathways: cAMP Metabolic Process