Sulfiredoxin 1 Antikörper (AA 45-137)

Produktnummer ABIN1387599

Produktdetails anti-Sulfiredoxin 1 Antikörper

Target: Sulfiredoxin 1 (SRX1)

Bindungsspezifität: AA 45-137

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sulfiredoxin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SRXN1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Sulfiredoxin 1 Antikörper (ABIN1387599)

Zhang, He, Guo, Li, Wang, Yang, Cui: "Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways." in: Bioscience reports, Vol. 36, Issue 2, (2016) (PubMed).

Zhou, Zhou, Yu, Wu, Chen, Zhao et al.: "Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ..." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 43-52, (2015) (PubMed).

Details zu Sulfiredoxin 1

Target: Sulfiredoxin 1 (SRX1)

Andere Bezeichnung: SRXN1 (SRX1 Produkte)

Synonyme: C20orf139 antikoerper, Npn3 antikoerper, SRX antikoerper, SRX1 antikoerper, Ab2-390 antikoerper, 1700127B04Rik antikoerper, AI854065 antikoerper, AW488194 antikoerper, Srx antikoerper, Srx1 antikoerper, TX01 antikoerper, sulfiredoxin 1 antikoerper, sulfiredoxin 1 homolog (S. cerevisiae) antikoerper, SRXN1 antikoerper, srxn1 antikoerper, Srxn1 antikoerper

Hintergrund:

Synonyms: SRX, Npn3, SRX1, C20orf139, Sulfiredoxin-1, SRXN1

Background: Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.

Gen-ID: 140809

UniProt: Q9BYN0