NCAM2 Antikörper (AA 51-150)

Produktnummer ABIN1387627

Produktdetails anti-NCAM2 Antikörper

Target: NCAM2 (Neural Cell Adhesion Molecule 2 (NCAM2))

Bindungsspezifität: AA 51-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCAM2 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCAM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NCAM2

Target: NCAM2 (Neural Cell Adhesion Molecule 2 (NCAM2))

Andere Bezeichnung: NCAM2 (NCAM2 Produkte)

Synonyme: NCAM21 antikoerper, Ncam-2 antikoerper, Ocam antikoerper, RNCAM antikoerper, zOCAM antikoerper, OCAM-GPI antikoerper, NCAM2 antikoerper, ncam21 antikoerper, neural cell adhesion molecule 2 antikoerper, zgc:152904 antikoerper, NCAM2 antikoerper, Ncam2 antikoerper, ncam2 antikoerper, LOC100471034 antikoerper, zgc:152904 antikoerper

Hintergrund:

Synonyms: N CAM 2, N CAM 21, N CAM2, N CAM21, N-CAM-2, NCAM 2, NCAM 21, NCAM-2, Ncam2, NCAM2_HUMAN, NCAM21, Neural cell adhesion molecule 2, OCAM GPI, R4B12, RB 8 neural cell adhesion molecule, RB8 neural cell adhesion molecule, RNCAM.

Background: NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2. NCAM2 contains five immunoglobulin-like domains, two Fibronectin type III domains, a transmembrane domain and a cytoplasmic domain. The gene is expressed most strongly in human adult and fetal brain. NCAM2 is a member of the neural cell adhesion molecule (NCAM) family. NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development. NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells. Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line, this binding is induced by cytokines that activate Stat5. Neither Stat1 nor Stat3 bind to this region, despite sharing a consensus binding sequence with Stat5.