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AASS Antikörper (AA 878-926)

AASS Reaktivität: Maus WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1387634
  • Target Alle AASS Antikörper anzeigen
    AASS (Aminoadipate Semialdehyde Synthase (AASS))
    Bindungsspezifität
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 878-926
    Reaktivität
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 16
    • 1
    • 1
    • 1
    Dieser AASS Antikörper ist unkonjugiert
    Applikation
    • 15
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LKRSDH
    Isotyp
    IgG
    Top Product
    Discover our top product AASS Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    AASS (Aminoadipate Semialdehyde Synthase (AASS))
    Andere Bezeichnung
    AASS/LKRSDH (AASS Produkte)
    Synonyme
    LKR/SDH antikoerper, LKRSDH antikoerper, LORSDH antikoerper, LKR antikoerper, LOR antikoerper, LOR/SDH antikoerper, Lorsdh antikoerper, SDH antikoerper, aminoadipate-semialdehyde synthase antikoerper, AASS antikoerper, Aass antikoerper
    Hintergrund

    Synonyms: Alpha aminoadipic semialdehyde synthase mitochondrial, LKR/SDH, LKRSDH, LORSDH, Lysine ketoglutarate reductase, Saccharopine dehydrogenase, AASS_HUMAN.

    Background: Alpha-aminoadipic semialdehyde synthase (AASS), also designated lysine ketoglutarate reductase (LKR) or saccharopine dehydrogenase (SDH), is a 926 amino acid protein that exists as a homodimer in the mitochondria. AASS acts as a bifunctional enzyme containing the lysine alpha-ketoglutarate reductase (LKR) and saccharopine dehydrogenase activities that catalyzes the first two steps in lysine degradation. It is widely expressed with highest expression in liver and transcription of the AASS gene is induced upon starvation. Mutations in the gene encoding AASS result in various forms familial hyperlysinemias (FH), autosomal recessive disorders characterized by hyperlysinemia, lysinuria, and variable saccharopinuria. However, no adverse mental or physical effects have been found in patients with hyperlysinemia.

    Gen-ID
    10157
    Pathways
    SARS-CoV-2 Protein Interaktom
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