SYT11 Antikörper (AA 51-100)

Produktnummer ABIN1387635

Produktdetails anti-SYT11 Antikörper

Target: SYT11 (Synaptotagmin XI (SYT11))

Bindungsspezifität: AA 51-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYT11 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Synaptotagmin XI

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SYT11

Target: SYT11 (Synaptotagmin XI (SYT11))

Andere Bezeichnung: Synaptotagmin 11 (SYT11 Produkte)

Synonyme: SYT12 antikoerper, sytXI antikoerper, 1500004A13Rik antikoerper, 3632445O20Rik antikoerper, 5430404N14Rik antikoerper, 6530420C11Rik antikoerper, AI851970 antikoerper, syt11 antikoerper, fc52d10 antikoerper, fi68d01 antikoerper, zgc:55556 antikoerper, wu:fc52d10 antikoerper, wu:fi68d01 antikoerper, SYT11 antikoerper, DKFZp459M023 antikoerper, synaptotagmin 11 antikoerper, synaptotagmin XI antikoerper, synaptotagmin XIa antikoerper, synaptotagmin XIb antikoerper, SYT11 antikoerper, Syt11 antikoerper, syt11a antikoerper, syt11 antikoerper, syt11b antikoerper

Hintergrund:

Synonyms: Synaptotagmin 11, Synaptotagmin 12, Synaptotagmin XI, Synaptotagmin-11, synaptotagmin XII, synaptotagmin-XII, Synaptotagmin11, Synaptotagmin12, Synaptotagmin-11, Synaptotagmin-12, SynaptotagminXI, SYT 11, SYT 12, SYT-11, SYT-12, Syt XI, Syt11, SYT11_HUMAN, SYT12, SytXI, DKFZp781D015, KIAA0080, MGC10881, MGC17226.

Background: Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XI, also known as SYT11 (Synaptotagmin-11), is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung. Like other Synaptotagmin proteins, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking. Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinson?s disease gene product), the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex. Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, including schizophrenia and Parkinson?s disease.

Gen-ID: 23208