MED17 Antikörper (AA 181-280)

Produktnummer ABIN1387677

Produktdetails anti-MED17 Antikörper

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Bindungsspezifität: AA 181-280

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRSP77

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Andere Bezeichnung: CRSP77 (MED17 Produkte)

Synonyme: crsp6 antikoerper, CRSP6 antikoerper, CRSP77 antikoerper, DRIP80 antikoerper, TRAP80 antikoerper, 77kDa antikoerper, C330002H14Rik antikoerper, Crsp6 antikoerper, Trap80 antikoerper, mediator of RNA polymerase II transcription subunit 17 antikoerper, mediator complex subunit 17 antikoerper, mediator complex subunit 17 L homeolog antikoerper, AOR_1_2446154 antikoerper, VDBG_01663 antikoerper, med17 antikoerper, med17.L antikoerper, MED17 antikoerper, Med17 antikoerper

Hintergrund:

Synonyms: CRSP6, CRSP77, DRIP80, TRAP80, Mediator of RNA polymerase II transcription subunit 17, Activator-recruited cofactor 77 kDa component, ARC77, Cofactor required for Sp1 transcriptional activation subunit 6, CRSP complex subunit 6, Mediator complex subunit 17, Thyroid hormone receptor-associated protein complex 80 kDa component, Transcriptional coactivator CRSP77, Vitamin D3 receptor-interacting protein complex 80 kDa component, MED17, DRIP77

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gen-ID: 9440

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha