TRIM54 Antikörper

Produktnummer ABIN1387738

Produktdetails anti-TRIM54 Antikörper

Target: TRIM54 (Tripartite Motif Containing 54 (TRIM54))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM54 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MURF3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TRIM54

Target: TRIM54 (Tripartite Motif Containing 54 (TRIM54))

Andere Bezeichnung: MURF3 (TRIM54 Produkte)

Synonyme: MGC80214 antikoerper, si:dkey-221h15.2 antikoerper, DKFZp468L1522 antikoerper, MURF antikoerper, MURF-3 antikoerper, RNF30 antikoerper, muRF3 antikoerper, 4930486E09Rik antikoerper, 4930566I02Rik antikoerper, MuRF3 antikoerper, Rnf30 antikoerper, tripartite motif containing 54 antikoerper, tripartite motif containing 54 S homeolog antikoerper, tripartite motif-containing 54 antikoerper, TRIM54 antikoerper, trim54.S antikoerper, trim54 antikoerper, Trim54 antikoerper

Hintergrund:

Synonyms: MURF 3, MURF, MURF-3, MuRF3, Muscle specic RING finger protein 3, Muscle specic RING finger protein, Muscle specic RING finger protein homolog, Muscle-specic RING finger protein 3, Muscle-specic RING finger protein, Ring finger protein 30, RNF30, TRI54_HUMAN, TRIM 54, TRIM54, RNF28, Tripartite mot containing 54, tibody Tripartite mot-containing protein 54.

Background: MuRF1, is a nuclear protein that interacts with SMT3b and the large myofibrillar protein Titin. In muscle cells, MuRF2 (RFN29) regulates gene expression and protein turnover. It localizes to the cytoplasm, but under atrophic conditions it is detected in the nucleus. MuRF2 can form oligomers with various other proteins, including Titin and Myosin. MuRF3, also designated tripartite motif-containing 54 (TRIM54) or ring finger protein 30 (RNF30), interacts with tubulin and stabilizes microtubules duing myotube formation. It is a cytoplasmic protein the localizes to the Z-lines in skeletal muscles, while MuRF2 localizes to the sarcomeric M-band in cardiomyocytes. MuRF3 shares 77 % and 65 % sequence identity with MuRF1 and MuRF2, respectively. MuRF1-3 share a conserved N-terminal RING domain and zinc-binding B-box motif, and two coiled-coil dimerization motif boxes, in their central regions.

Gen-ID: 57159