CHRND Antikörper (AA 145-190)

Produktnummer ABIN1387797

Produktdetails anti-CHRND Antikörper

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Bindungsspezifität: AA 145-190

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRND Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHRND

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CHRND

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Andere Bezeichnung: CHRND (CHRND Produkte)

Synonyme: ACHRD antikoerper, CMS2A antikoerper, FCCMS antikoerper, SCCMS antikoerper, wu:fa01e01 antikoerper, zgc:110469 antikoerper, CHNRD antikoerper, MGC97613 antikoerper, Achr-4 antikoerper, Acrd antikoerper, L10076 antikoerper, chnrd antikoerper, chrng antikoerper, cholinergic receptor nicotinic delta subunit antikoerper, cholinergic receptor, nicotinic, delta (muscle) antikoerper, cholinergic receptor, nicotinic, delta antikoerper, cholinergic receptor nicotinic gamma subunit antikoerper, cholinergic receptor, nicotinic delta antikoerper, cholinergic receptor, nicotinic, delta polypeptide antikoerper, cholinergic receptor, nicotinic delta L homeolog antikoerper, CHRND antikoerper, chrnd antikoerper, CHRNG antikoerper, Chrnd antikoerper, chrnd.L antikoerper

Hintergrund:

Synonyms: Acetylcholine receptor delta subunit, Acetylcholine receptor subunit delta, ACHD_HUMAN, ACHRD, Cholinergic receptor, nicotinic, delta polypeptide, CHRND, CMS2A, FCCMS, Nicotinic acetylcholine receptor delta polypeptide precursor, SCCMS.

Background: Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChR delta, also known as CMS2A, FCCMS, SCCMS or CHRND, is a 517 amino acid multi-pass membrane protein that is associated with lethal type multiple pterygium syndrome, congenital myasthenic syndrome slow-channel type (SCCMS) and congenital myasthenic syndrome fast-channel type (FCCMS).