Contactin 5 Antikörper (AA 801-900)
Kurzübersicht für Contactin 5 Antikörper (AA 801-900) (ABIN1387811)
Target
Alle Contactin 5 (CNTN5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 801-900
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Homologie
- Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Contactin 5
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- Contactin 5 (CNTN5)
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Andere Bezeichnung
- CNTN5/Contactin 5
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Hintergrund
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Synonyms: Contactin5, Contactin-5, hNB 2, HNB 2s, NB 2, Neural recognition molecule NB 2, CNTN5_HUMAN.
Background: Changes in synaptic efficacy can mediate crucial processes during learning and memory formation. Accumulating evidence implicates cell adhesion molecules in activity-dependent synaptic modifications associated with paired-pulse facilitation (PPF), long-term potentiation (LTP) and long-term depression (LTD). Among the cell adhesion molecules involved in these processes are the contactins. Contactins are immunoglobulin superfamily members that play a selective role in synaptic plasticity, PPF and LTD, and may regulate cell-cell interactions contributing to synaptic plasticity in conjunction with other synapse targeting molecules, including paranodin and phosphacan. In addition, contactins are essential components that control expression and distribution of Na+ channels in neurons, junctional attachment at the paranode, and ultimately the physiology of the myelinated nerve. The human Contactin 1 gene encodes a 1,018 amino acid protein. The human Contactin 3 gene encodes a 646 amino acid plasmacytoma-associated neuronal glycoprotein. The human Contactin 5 gene encodes a 1,100 amino acid neural adhesion molecule. The human Contactin 6 gene encodes a 1,028 amino acid neural adhesion molecule.
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Gen-ID
- 53942
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Pathways
- Sensory Perception of Sound
Target
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