BCL11A Antikörper (AA 751-835)

Produktnummer ABIN1387845

Produktdetails anti-BCL11A Antikörper

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Bindungsspezifität: AA 751-835

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ctip1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu BCL11A

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Andere Bezeichnung: Ctip1/BCL-11A (BCL11A Produkte)

Synonyme: 2810047E18Rik antikoerper, BCL-11A antikoerper, Ctip1 antikoerper, D930021L15Rik antikoerper, Evi9 antikoerper, Evi9a antikoerper, Evi9b antikoerper, Evi9c antikoerper, mKIAA1809 antikoerper, BCL11A-L antikoerper, BCL11A-S antikoerper, BCL11A-XL antikoerper, BCL11a-M antikoerper, CTIP1 antikoerper, EVI9 antikoerper, HBFQTL5 antikoerper, ZNF856 antikoerper, bcl11a antikoerper, wu:fi09f10 antikoerper, zgc:136898 antikoerper, B cell CLL/lymphoma 11A (zinc finger protein) antikoerper, B-cell CLL/lymphoma 11A antikoerper, B-cell CLL/lymphoma 11A L homeolog antikoerper, B-cell CLL/lymphoma 11Aa antikoerper, Bcl11a antikoerper, BCL11A antikoerper, bcl11a.L antikoerper, bcl11aa antikoerper

Hintergrund:

Synonyms: B cell CLL/lymphoma 11A zinc finger protein, B cell CLL/lymphoma 11A zinc finger protein isoform 2, B cell CLL/lymphoma 11A, B cell lymphoma/leukaemia 11A, B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BC11A_HUMAN, BCL 11A, BCL-11A, BCL11A, BCL11A B cell CLL/lymphoma 11A zinc finger protein isoform 1, BCL11A L, BCL11A S, BCL11A XL, BCL11AL, BCL11AS, BCL11AXL, C2H2 type zinc finger protein, COUP TF interacting protein 1, COUP-TF-interacting protein 1, Ctip 1, CTIP1, Ecotropic viral integration site 9, Ecotropic viral integration site 9 homolog, Ecotropic viral integration site 9 protein, Ecotropic viral integration site 9 protein homolog, Evi 9, EVI-9, Evi9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, Zinc finger protein 856, ZNF856.

Background: Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

Pathways: Regulation of Cell Size