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MSH3 Antikörper (AA 521-620)

MSH3 Reaktivität: Human, Maus, Ratte WB, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1387851
  • Target Alle MSH3 Antikörper anzeigen
    MSH3 (MutS Homolog 3 (MSH3))
    Bindungsspezifität
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 521-620
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 33
    • 1
    Kaninchen
    Klonalität
    • 33
    • 1
    Polyklonal
    Konjugat
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MSH3 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 12
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MSH3
    Isotyp
    IgG
    Top Product
    Discover our top product MSH3 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MSH3 (MutS Homolog 3 (MSH3))
    Andere Bezeichnung
    MSH3 (MSH3 Produkte)
    Synonyme
    ATMSH3 antikoerper, M7J2.90 antikoerper, M7J2_90 antikoerper, homolog of DNA mismatch repair protein MSH3 antikoerper, DUP antikoerper, MRP1 antikoerper, D13Em1 antikoerper, Rep-3 antikoerper, Rep3 antikoerper, mutS homolog 3 antikoerper, DNA mismatch repair protein MSH3 antikoerper, homolog of DNA mismatch repair protein MSH3 antikoerper, mismatch repair protein antikoerper, MSH3 antikoerper, Msh3 antikoerper
    Hintergrund

    Synonyms: DUP, MRP1, DNA mismatch repair protein Msh3, hMSH3, Divergent upstream protein, Mismatch repair protein 1, MSH3, DUC1, DUG

    Background: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

    Gen-ID
    4437
    UniProt
    P20585
    Pathways
    DNA Reparatur, Production of Molecular Mediator of Immune Response
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