alpha 2 Macroglobulin Antikörper

Produktnummer ABIN1387864

Produktdetails anti-alpha 2 Macroglobulin Antikörper

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reaktivität: Human, Ratte, Maus, Huhn, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha 2 Macroglobulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Huhn, Rind (Kuh), Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human alpha 2 Macroglobulin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-alpha 2 Macroglobulin Antikörper (ABIN1387864)

Liu, Wang, Liu, Wang, Zheng, Tan, Xing, Cui, Li, Zhao, Wen: "Uncovering the embryonic development-related proteome and metabolome signatures in breast muscle and intramuscular fat of fast-and slow-growing chickens." in: BMC genomics, Vol. 18, Issue 1, pp. 816, (2017) (PubMed).

Shu, Bai, Wang, Xiao, Fan, Zhang, Zhao, Zhao, Xia, Zhang: "Differentially expressed serum proteins associated with calcium regulation and hypocalcemia in dairy cows." in: Asian-Australasian journal of animal sciences, Vol. 30, Issue 6, pp. 893-901, (2017) (PubMed).

Hu, Lin, Zhu, Li, Chen: "Anti-inflammatory effects of Gualou Guizhi decoction in transient focal cerebral ischemic brains. [Corrected]." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 3998, (2015) (PubMed).

Details zu alpha 2 Macroglobulin

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Andere Bezeichnung: alpha 2 Macroglobulin (A2M Produkte)

Hintergrund:

Synonyms: A2M, A2MG_HUMAN, Alpha 2 M, Alpha 2M, Alpha-2-M, Alpha-2-macroglobulin, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, CPAMD5, DKFZp779B086, FWP007, S863 7.

Background: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008].

Gen-ID: 2

Pathways: Lipid Metabolism