Transportin 1 Antikörper

Produktnummer ABIN1387906

Produktdetails anti-Transportin 1 Antikörper

Target: Transportin 1 (TNPO1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transportin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Transportin 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Transportin 1

Target: Transportin 1 (TNPO1)

Andere Bezeichnung: Transportin 1 (TNPO1 Produkte)

Synonyme: IPO2 antikoerper, KPNB2 antikoerper, MIP antikoerper, MIP1 antikoerper, TRN antikoerper, TNPO1 antikoerper, AU021749 antikoerper, D13Ertd688e antikoerper, Kpnb2 antikoerper, ATTRN1 antikoerper, F12A24.13 antikoerper, F12A24_13 antikoerper, TRANSPORTIN 1 antikoerper, transportin 1 antikoerper, DKFZp469O204 antikoerper, transportin 1 antikoerper, transportin-1 antikoerper, transportin 1 S homeolog antikoerper, TNPO1 antikoerper, LOC738932 antikoerper, tnpo1 antikoerper, Tnpo1 antikoerper, tnpo1.S antikoerper, TRN1 antikoerper

Hintergrund:

Synonyms: Importin 2, Importin beta 2, IPO 2, IPO2, Karyopherin importin beta 2, Karyopherin beta 2, KPN B2, KPNB 2, KPNB2, M9 interacting protein, M9 region interacting protein, M9 region interaction protein, M9-interacting protein, MIP 1, MIP, MIP1, TNPO 1, TNPO1, Transportin 1, Transportin, Transportin-1, Transportin1, TRN, TNPO1_HUMAN.

Background: Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.

Gen-ID: 3842

Pathways: PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events