DLGAP1 Antikörper (AA 241-360)

Produktnummer ABIN1387960

Produktdetails anti-DLGAP1 Antikörper

Target: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Bindungsspezifität: AA 241-360

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLGAP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAPAP1/DLGAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DLGAP1

Target: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Andere Bezeichnung: SAPAP1/DLGAP1 (DLGAP1 Produkte)

Hintergrund:

Synonyms: PSD95 binding protein 1, DAP 1 ALPHA, DAP 1, DAP 1 BETA, DAP-1, DAP-1-ALPHA, DAP-1-BETA, DAP1, Discs large Drosophila homolog associated protein 1, Discs large homolog associated protein 1, Disks large associated protein 1, Disks large associated protein 1, alpha isoform, included, Disks large associated protein 1, beta isoform, included, Disks large-associated protein 1, DLGAP 1, Dlgap1, DLGP1_HUMAN, GKAP, GKAP/SAPAP, GKPA/SAPAP, Guanylate kinase associated protein, Guanylate kinase-associated protein, hGKAP, KIAA4162, MGC88156, mKIAA4162, PSD 95/SAP90 binding protein 1, PSD-95/SAP90-binding protein 1, SAP90/PSD 95 associated protein 1, SAP90/PSD-95-associated protein 1, SAPAP 1, SAPAP1.

Background: Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-a, DAP-1-b, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP, through the guanylate kinase domain. GKAP is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. GKAP is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.