Ferric-Chelate Reductase 1 Like (FRRS1L) Antikörper

Produktnummer ABIN1387966

Produktdetails

Target: Ferric-Chelate Reductase 1 Like (FRRS1L)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Brain protein CG6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Ferric-Chelate Reductase 1 Like (FRRS1L)

Andere Bezeichnung: Brain protein CG6 (FRRS1L Produkte)

Synonyme: C9orf4 antikoerper, CG-6 antikoerper, CG6 antikoerper, 6430704M03Rik antikoerper, ferric chelate reductase 1 like antikoerper, ferric-chelate reductase 1 like antikoerper, FRRS1L antikoerper, Frrs1l antikoerper

Hintergrund:

Synonyms: Brain protein CG 6, Brain protein CG-6, Brain protein CG6, C9orf4, CG 6, CG6, chromosome 9 open reading frame 4, CI004_HUMAN, Uncharacterized protein C9orf4.

Background: C9orf4 is a 344 amino acid single-pass membrane protein that is primarily expressed in adult and fetal brain and is weakly expressed in spinal cord, adult ovary and medulla. C9orf4 contains one DOMON domain, a predominantly _-sheet domain that is thought to aide in extracellular adhesion. The gene encoding C9orf4 maps to human chromosome 9, which consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.