BFSP2 Antikörper (AA 181-280) (Biotin)

Produktnummer ABIN1388779

Produktdetails anti-BFSP2 Antikörper (Biotin)

Target: BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))

Bindungsspezifität: AA 181-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BFSP2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BFSP2/Phakinin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu BFSP2

Target: BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))

Andere Bezeichnung: Bfsp2/Phakinin (BFSP2 Produkte)

Synonyme: CP47 antikoerper, CP49 antikoerper, CTRCT12 antikoerper, LIFL-L antikoerper, PHAKOSIN antikoerper, AI448593 antikoerper, CP49INS antikoerper, BFSP2 antikoerper, LOC100222605 antikoerper, Bfsp2 antikoerper, zgc:103750 antikoerper, beaded filament structural protein 2 antikoerper, beaded filament structural protein 2, phakinin antikoerper, BFSP2 antikoerper, Bfsp2 antikoerper, bfsp2 antikoerper

Hintergrund:

Synonyms: 49 kDa cytoskeletal protein, Beaded filament protein CP49, Beaded filament structural protein 2, Beaded filament structural protein 2, phakinin, Bfps2, Cytoskeletal protein, 49 kD, BFSP2, BFSP2_HUMAN, CP47, CP49, Lens fiber cell beaded filament protein CP 47, Lens fiber cell beaded filament protein CP 49,Lens intermediate filament-like light, LL-L, Phakinin, PHAKOSIN.

Background: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.

Gen-ID: 3921