CRIPT Antikörper (AA 21-80) (AbBy Fluor® 647)

Produktnummer ABIN1388802

Produktdetails anti-CRIPT Antikörper (AbBy Fluor® 647)

Target: CRIPT (Cysteine-Rich PDZ-Binding Protein (CRIPT))

Bindungsspezifität: AA 21-80

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRIPT Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRIPT

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CRIPT

Target: CRIPT (Cysteine-Rich PDZ-Binding Protein (CRIPT))

Andere Bezeichnung: CRIPT (CRIPT Produkte)

Synonyme: CRIPT antikoerper, hspc139 antikoerper, cript antikoerper, im:7137989 antikoerper, zgc:110618 antikoerper, 1200020A08Rik antikoerper, AA589469 antikoerper, CXXC repeat containing interactor of PDZ3 domain antikoerper, cysteine-rich PDZ-binding protein antikoerper, CXXC repeat containing interactor of PDZ3 domain S homeolog antikoerper, CRIPT antikoerper, cript antikoerper, LOC725850 antikoerper, cript.S antikoerper, Cript antikoerper

Hintergrund:

Synonyms: CRIPT, CRIPT_HUMAN, Cysteine rich interactor of PDZ3, Cysteine rich PDZ binding protein, Cysteine-rich interactor of PDZ three, Cysteine-rich interactor of PDZ3, Cysteine-rich PDZ-binding protein, HSPC139, HSPC139 protein, Hypothetical protein CRIPT, Postsynaptic protein CRIPT.

Background: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. These proteins are physically and functionally linked to cytoskeletal and/or signaling proteins. CRIPT (for cysteine-rich interactor of PDZ three), a novel postsynaptic protein, binds specifically to the PDZ3 domain of PSD-95/SAP 90. CRIPT induces the recruitment of PSD-95/SAP 90 to microtubules, and it has been shown to bind directly to microtubules, indicating that it may be responsible for cytoskeletal anchoring of PSD-95/SAP 90. CRIPT is widely expressed outside of the brain and is highly conserved from animals to plants suggesting a wider role in regulating cytoskeleton-membrane associations.