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OTOA Antikörper (AA 231-330) (FITC)

OTOA Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN1389032
  • Target Alle OTOA Antikörper anzeigen
    OTOA (Otoancorin (OTOA))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    • 1
    AA 231-330
    Reaktivität
    • 29
    • 4
    Maus
    Wirt
    • 29
    • 1
    Kaninchen
    Klonalität
    • 29
    • 1
    Polyklonal
    Konjugat
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser OTOA Antikörper ist konjugiert mit FITC
    Applikation
    • 30
    • 16
    • 13
    • 12
    • 12
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human OTOA/DFNB22
    Isotyp
    IgG
    Top Product
    Discover our top product OTOA Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    OTOA (Otoancorin (OTOA))
    Andere Bezeichnung
    OTOA/DFNB22 (OTOA Produkte)
    Synonyme
    CT108 antikoerper, DFNB22 antikoerper, RGD1562741 antikoerper, otoancorin antikoerper, otoancorin L homeolog antikoerper, OTOA antikoerper, otoa.L antikoerper, otoa antikoerper, Otoa antikoerper
    Hintergrund

    Synonyms: Cancer/testis antigen 108, CT108, Deafness, autosomal recessive 22, DFNB22, OTOA, OTOAN_HUMAN, Otoancorin.

    Background: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.

    Gen-ID
    146183
    UniProt
    Q7RTW8
    Pathways
    Sensory Perception of Sound
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