PCDHb4 Antikörper (AA 251-350) (AbBy Fluor® 647)

Produktnummer ABIN1389498

Produktdetails anti-PCDHb4 Antikörper (AbBy Fluor® 647)

Target: PCDHb4 (Protocadherin beta 4 (PCDHb4))

Bindungsspezifität: AA 251-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHb4 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PCDHb4

Target: PCDHb4 (Protocadherin beta 4 (PCDHb4))

Andere Bezeichnung: PCDHB4 (PCDHb4 Produkte)

Synonyme: PCDH-BETA4 antikoerper, Pcdhb5A antikoerper, PcdhbD antikoerper, protocadherin beta 4 antikoerper, PCDHB4 antikoerper, Pcdhb4 antikoerper

Hintergrund:

Synonyms: PCDB4_HUMAN, PCDH beta4, PCDH-beta-4, PCDHB4, PCDHB 4, PCDHB-4, Pcdhb5A, PcdhbD, Protocadherin beta-4.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB4 (Protocadherin beta-4) is a 795 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB4) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB4 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain.