Chromosome 11open Reading Frame 9 (C11orf9) (AA 401-500) Antikörper (AbBy Fluor® 488)
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- Target Alle Chromosome 11open Reading Frame 9 (C11orf9) Antikörper anzeigen
- Chromosome 11open Reading Frame 9 (C11orf9)
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Bindungsspezifität
- AA 401-500
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MYRF
- Isotyp
- IgG
- Top Product
- Discover our top product C11orf9 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Chromosome 11open Reading Frame 9 (C11orf9)
- Andere Bezeichnung
- MYRF/C11orf9 (C11orf9 Produkte)
- Synonyme
- C11orf9 antikoerper, c11orf9 antikoerper, mrf antikoerper, ndt80 antikoerper, MRF antikoerper, Ndt80 antikoerper, pqn-47 antikoerper, 6030439E18 antikoerper, Gm1804 antikoerper, Gm98 antikoerper, Mrf antikoerper, chromosome 5 open reading frame, human C11orf9 antikoerper, myelin regulatory factor L homeolog antikoerper, myelin regulatory factor antikoerper, C5H11ORF9 antikoerper, myrf.L antikoerper, MYRF antikoerper, Myrf antikoerper
- Hintergrund
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Synonyms: MRF, Ndt80, pqn-47, C11orf9, Myelin regulatory factor, Myelin gene regulatory factor, MYRF, KIAA0954
Background: Myelin regulatory factor: Consitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype (PubMed:23966832).
- Gen-ID
- 745
- UniProt
- Q9Y2G1
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