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Chromosome 11open Reading Frame 9 (C11orf9) (AA 401-500) Antikörper (Biotin)

C11orf9 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1389817
  • Target Alle Chromosome 11open Reading Frame 9 (C11orf9) Antikörper anzeigen
    Chromosome 11open Reading Frame 9 (C11orf9)
    Bindungsspezifität
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 401-500
    Reaktivität
    • 23
    • 19
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 25
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biotin
    Applikation
    • 19
    • 13
    • 13
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MYRF
    Isotyp
    IgG
    Top Product
    Discover our top product C11orf9 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Chromosome 11open Reading Frame 9 (C11orf9)
    Andere Bezeichnung
    MYRF/C11orf9 (C11orf9 Produkte)
    Synonyme
    C11orf9 antikoerper, c11orf9 antikoerper, mrf antikoerper, ndt80 antikoerper, MRF antikoerper, Ndt80 antikoerper, pqn-47 antikoerper, 6030439E18 antikoerper, Gm1804 antikoerper, Gm98 antikoerper, Mrf antikoerper, chromosome 5 open reading frame, human C11orf9 antikoerper, myelin regulatory factor L homeolog antikoerper, myelin regulatory factor antikoerper, C5H11ORF9 antikoerper, myrf.L antikoerper, MYRF antikoerper, Myrf antikoerper
    Hintergrund

    Synonyms: MRF, Ndt80, pqn-47, C11orf9, Myelin regulatory factor, Myelin gene regulatory factor, MYRF, KIAA0954

    Background: Myelin regulatory factor: Consitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype (PubMed:23966832).

    Gen-ID
    745
    UniProt
    Q9Y2G1
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