LRRTM1 Antikörper (AA 151-250) (Biotin)

Produktnummer ABIN1389943

Produktdetails anti-LRRTM1 Antikörper (Biotin)

Target: LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))

Bindungsspezifität: AA 151-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRTM1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRRTM1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu LRRTM1

Target: LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))

Andere Bezeichnung: LRRTM1 (LRRTM1 Produkte)

Synonyme: im:6904481 antikoerper, 4632401D06Rik antikoerper, AW125451 antikoerper, leucine rich repeat transmembrane neuronal 1 antikoerper, lrrtm1 antikoerper, LRRTM1 antikoerper, Lrrtm1 antikoerper

Hintergrund:

Synonyms: Leucine rich repeat transmembrane neuronal 1, Leucine rich repeat transmembrane neuronal 1 protein, Leucine-rich repeat transmembrane neuronal protein 1, LRRT1_HUMAN, LRRTM1, Lrrtm1 leucine rich repeat transmembrane neuronal 1, OTTHUMP00000194829, 4632401D06Rik, AW125451, FLJ32082.

Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRR repeats. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96 % amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders.

Pathways: Synaptic Membrane